Just installed Big Sur macOS on my iMac. Tested standalones for Topaz Apps.
JPEG to RAW AI will not start. I reported this as a bug to Topaz Support.
Topaz Adjust AI will not start, and it will not run as a plugin in Affinity Photo. (I have not reported this yet but will).
Topaz Studio 2 auto updater gives a false report of available update. To get it to run, you have to dismiss the update popup.