Please follow the instructions here to run the installer in the Admin Command Prompt.
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Search for Command Prompt. Click run as Administrator
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Follow the instructions here to get the directory for your Downloads folder | Running Topaz Photo AI Installer with Admin Command Prompt Windows | Loom
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Type in the below command and then hit Enter to run the Topaz Photo AI installer. Make sure the name of the installer in the command matches the one in your Downloads folder.msiexec /i TopazPhotoAI-3.3.1.msi