Do Topaz Filters hurt end product for print?

Quick question:
Sometimes when using topaz studio and playing with the various filters, when I zoom up close to 100%, I can see strange bits of picture – does this hurt the final resolution output when it goes to print? I’m a commercial artist and I don’t want to be hurting my work – but just wondering if there’s a way to clean it up a bit after the filters have been applied so that the print is good.

Thanks in advance for your help!