In order to upscale an image, the image must be processed after the preview with the Export Image button.
The preview is just that, a preview of what the image will appear as after processing/creating/saving.
You will not be able to simply copy the image from the preview as the image has no been enhanced/upscaled at this point.
We do have a list of available shortcut commands. You can find these commands by opening the Gigapixel > Preferences dropdown menu.

Your recommendation is acheiveable, but you must specify that the original file should be overwritten after processing within your Export settings like I listed in my previous response.
By default, Gigapixel will not overwrite the original file and your workflow is not achievable as you’ll need to adjust the clipboard image to the newly create file after export.
I have brought up this idea to our development team for future consideration.

