If you’re really serious about getting the best possible result, then you could mitigate that issue by splitting up your clip. I haven’t yet gone that far with mine, but I’m considering it, because I really want to turn up sharpening, deblur and detail recovery on the close-up shots, but turn them down on zoomed out shots where those parameters introduce some horrendous looking artifacts.
Also if you’re doing multiple upscales with Topaz then you should ideally output as images because the approach that Topaz uses to encode your video results in quite poor quality compared to doing it yourself. If you’re going to feed the output back into Topaz then you end up unecessarily losing quality if you let Topaz encode after the first pass.
Just doing a simple
-preset slower with ffmpeg I found that I was getting an mp4 half the size of what Topaz gave me, and in better quality. Fortunately this is something that the beta is now giving us control over, but for the current release version you are stuck with Topaz’s default which isn’t great.