Studio and Gigapixel Issues Opening

Strange issue. Studio 2 and Gigapixel worked fine and the Apps opened with no issues. Windows 11. Bought a Prograde CFExpress Card reader to use with my CFExpress card. Since plugging in the reader into a USB port neither Studio or Gigapixel apps will open unless a CFExpress card is inserted in the reader. Tried uninstalling Studio and Gigapixel and reinstalling. Same thing. Not sure where to turn now.