For certain files when I edit them from Lightroom with File → Plug-in Extras → Process with Topaz Photo AI, the new .dng file gets corrupted back in Lightroom, and I have to restart Lightroom, and change to tif processing instead of RAW.
Do you have antivirus or any security applications that could be preventing Topaz Photo AI from writing the file correctly?
I processed the file on my computer and it imported to Lightroom Classic and Photoshop without issue.
Please upload the output DNG and I can take a look at it. You can securely submit your image(s) to my Dropbox using the link below. Please be sure to send me a note to let me know you sent something. Dropbox File Request