A DNG created by any application as output is not a RAW file and does not contain original sensor data… The problems with any DNG is that it has its own profile which may or may not be interpreted by other applications.
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I had the same problem with my Canon 80d’s .cr2 files.
The best solution I found was:
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Import all original .cr2 files into Lightroom
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Turn off all Lightroom adjustments, for the best Topaz AI results
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Select all imported files and with the settings disabled, right-click and select the Edit In>Topaz AI option, in this way Topaz will receive the files in the .tiff extension and keep all the metadata
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Make adjustments in Topaz AI to your liking and save, Topaz AI will duplicate all Lightroom files with noiseless copies
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Delete the original files with noise from Lightroom, and follow the workflow normally with the files created by Topaz that keep the metadata and have no problems with colors, the generated files are exactly identical to the originals but with the noise correction
I don’t recall seeing the problem in current versions of the software. But, your approach is interesting, though drastically different than what I typically do with RAW images.
