I've only used all Topaz Products from within Lightroom using 'Edit in..." How do I access Topaz from within Photoshop?

Today, I have a Focus-stacked image in Photoshop which I’ve saved now as one layer and want to now run it through Topaz AI but don’t know the proper workflow. I tried opening the saved Photoshop document from within Topaz AI but the file is grayed out and I assume Topaz wants me to save that document as a TIFF? I would just like to know as Topaz works beautifully from within Lightroom and returns me back to Lightroom after a file is processed. Photoshop has no ‘Edit In…’ menu dialog so I need professional technical help with this so I start off on the right foot. I want the highest quality so ask for help here. TIA, Ken