Getting stuttering on video output with 8 streams of audio

I’ve been having issues with output video stuttering on a 4k upres. The pattern is about every 5 seconds on the output video it appears to skip. I’m seeing the same number of frames on output and a larger jump on the individual frame that is the culprit.

This video has 8 audio streams in it and am wondering if this is tripping it up. Has anyone had success with topaz and more then 2 audio streams? This is a pro res file that’s under a gb.