In the middle of running Photo Ai using sharpening v.2 and upscaling 2x the process aborted twice and knocked out PS. I do not think this was a PS issue. Please check to see that upscaling works with PS as it is supposed to do in version 2.0.2.
To use the Upscale filter in the PS plugin, please use the File > Automate workflow rather than the File > Plug-in Extras > Process with Topaz Photo AI workflow.
Thanks for sharing. Can you actually submit a support ticket at support.topazlabs.com using the beacon at the bottom right corner of the page? We’ll be able to help you out faster there using specific info about your computer and images.