Something that just occurred to me is a deep map sharpening.
Let’s say I have two people, one of them in piggyback, I have photographed with an open aperture of 2.0 or 1.4, the camera has targeted the person in front by pulling along, but has pulled too far forward, the person on the back of the other is a bit out of focus.
If I now sharpen with PhotoAI using the standard filter, the person in front may be too sharp.
With a depth map you could reduce the oversharpening of the person in front.
You could “sharpen” your image in Topaz, and then use Lightroom’s tool to move the focus just a tad in in front of the “over-sharpened” front person. Before you poopoo the Adobe tool, have you used it?