Please open Topaz Photo AI, go to the menu bar on the top and click the Help > Open Log Folder menu option. Attach the logs files that you can see in the window that opens.
I should be able to determine what is happening and send next steps with this information.
Please send me the logs by attaching them here or uploading to my Dropbox. You can securely submit your image(s) to my Dropbox using the link below. Please be sure to send me a note to let me know you sent something. Dropbox File Request
If you do not have logs, then please visit this page, select your operating system (Windows or Mac) and click “Find Your System Profile”. Send me the system profile so I can check your system specs. Topaz Photo AI System Requirements